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Funding This manuscript was supported by the National Natural Science Foundation of China (Grant number: 32100925, 82027802), the Beijing Nova Program (Grant number: Z211100002121038), the Beijing Hundred Thousand and Ten Thousand Talent Project (Grant number: 2019A36), and the Beijing Municipal Health Commission (Grant number: 30301005-0019)

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Zepbound (tirzepatide) is a prescription medication that has been FDA-approved for adults with obesity or those who are overweight with at least one weight-related health condition