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Figure 7C shows that most of RGD-GHK was concentrated on the epidermal layer, while only a few GHK and sOtx2-GHK were observed on the skin layer

Consistently, inhibition of cellular cysteine uptake by using erastin (an inhibitor of system x c ) depleted GSH and induced ferroptosis 19

Though some side effects are mild, they can negatively affect the drugs efficacy and patient tolerance, research has found

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Bora S, et al