The most recent Phase 3 trial showed discontinuation rates of 12-18% due to adverse events, higher than existing GLP-1 medications
Tirzepatide is administered subcutaneously, meaning into the fat layer just beneath the skin, not into muscle
Reflects evidence : Clinical analogs of semaglutide (e.g., RYBELSUS) have demonstrated significant reductions in HbA1c and body weight in clinical studies
Related Reading Oral Semaglutide 2 Semaglutide Providers That Take Fsa Plexusdx Oral Semaglutide Vs Injectable Vs Plexusdx Oral Semaglutide For Type 2 Diabetes Pricing and availability current as of June 2026
This translates to each portion of the medication being 0.025 mg, and knowing how to convert these measurements accurately is essential for both patients and healthcare providers, particularly when determining that 100 units of semaglutide is how many mg, helping to ensure proper dosing and prevent potential overdoses or underdoses
This comparison matters because many people consider Pendulum specifically as an alternative to medications like semaglutide and tirzepatide
