This is one of the reasons it is different from GLP-1-only treatments
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Any medicines that are bought outside of the legal supply chain: May not contain any active ingredient
Retatrutide is an investigational triple agonist that simultaneously activates GLP-1, GIP, and glucagon receptors, enhancing insulin secretion, suppressing appetite, increasing energy expenditure, and promoting hepatic fat oxidation
After two years, the discontinuation rates rise to 84% for non-diabetic patients and 64% for diabetics
The short answer: some lean mass loss occurs, as it does with any caloric deficit, but the proportion is better than diet-alone approaches