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1 Introduction Metabolic syndrome (MS) is a worldwide healthcare issue of increasing magnitude, with the number of cases projected to reach approximately 2.568 billion by 2040 ( In addition to active intervention and improvement of the patients lifestyle, the clinical treatment of MS focuses on individual or combined drug therapy for specific pathologic features to achieve reduction of insulin resistance, restoration of normal blood glucose, improvement of lipid metabolism disorders, and lowering of blood pressure

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The most frequently reported symptoms include nausea, vomiting, decreased appetite, and mild abdominal discomfort