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You may lose less weight than expected on semaglutide due to: Sedentary lifestyle Skipping or missing the doses Medical conditions such as hypothyroidism, PCOS, or insulin resistance can also affect the progress Plateau phase Slow metabolism Unhealthy eating habits What if Im not losing weight by month 3
So, hit the gym and get a good variety of activities throughout the week
Importantly, adipose inflammatory responses and Tir sensitivity differed substantially between fat depots
Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities
