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In the Phase 3 TRIUMPH-4 trial, participants on the highest dose (12 mg) lost an average of 28.7% of their body weight over 68 weeks

Our newest publication explores a possible side effect some patients may experience on higher doses of tirzepatide: reduced motivation or "anhedonia-like" symptoms

Patient harm from compounded weight loss shots According to a civil complaint filed against Empower Pharmacy, a 50-year-old Texan woman spent weeks in the hospital and died in 2024 after using untested compounded semaglutide/cyanocobalamin injections as prescribed by the compounder

Polycystic ovaries Individuals with PCOS usually have enlarged ovaries that contain numerous small cysts (visible on an ultrasound)

Wait for about 24 hours after the first dose before using another

Citrulline is an amino acid that was first isolated from watermelon, Citrullus vulgaris