doi:10.1136/bmjopen-2012-001986., Edwards CM, Todd JF, Ghatei MA, Bloom SR: Subcutaneous glucagon-like peptide-1 (7-36) amide is insulinotropic and can cause hypoglycaemia in fasted healthy subjects
(25% of body weight), compared to 1.5% on placebo, according to data not controlled for type 1 error
Over the last few years, the popularity of Type 2 diabetes medications like Ozempic and Mounjaro are sometimes prescribed off label for weight loss, while Wegovy and Zepbound are approved for the treatment of obesity
The liraglutide doses were administered once a day subcutaneously
doi: 10.1016/S0140-6736(23)01185-6
Now, scientists are exploring whether those powerful effects could translate into a treatment for binge eating disorder, the most common eating disorder in the United States