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Despite being water soluble, vitamin B12 is stored in the liver in substantial amounts (25 mg) that can sustain normal function for 35 years
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This review focuses on the search for the most optimal animal model for the preclinical study and the subsequent use of the selected models for other new investigational substances, in particular SEGRA, where GCs act as a positive control
doi: 10.1038/s41598-019-44816-w 157 SatoD.LionelA
It is indicated for blood sugar control in patients with type 2 diabetes mellitus, either as a monotherapy or in combination with other glucose-lowering drugs
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