My suspicion would be that any benefit that somebody got from this would be much more likely due to a placebo effect than actual increased production of GLP-1, says Dr
GLP-1R activation has a significant effect on glycemic control in patients with T2DM through a variety of mechanisms, including stimulation of insulin secretion, inhibition of glucagon secretion, protection of -cells from apoptosis, slowing gastric emptying and increasing satiety (Drucker, 2006)
J Cell Physiol 230:30093018 [DOI] [PubMed] [Google Scholar] 62.Yu J, Shi YC, Ping F, Li W, Zhang HB, He SL, Zhao Y, Xu LL, Li YX (2021) Liraglutide inhibits osteoclastogenesis and improves bone loss by downregulating Trem2 in female type 1 diabetic mice: findings from transcriptomics
doi: 10.1053/j.gastro.2004.04.063 27 SmitsMMTonneijckLMuskietMHAKramerMHHCahenDLvan RaalteDH
Recent insights into GLP-1R signaling in beta cells is summarized in (115)
Habener drew on the skills of several young researchers
