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CFTR expression, in contrast, is known to be highest in crypt cells, with a gradient decreasing towards the villi tips 97,98,99 , consistent with our observations of CFTR expression in ISCs (Supplementary Fig

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[DOI] [PubMed] [Google Scholar] 124.Ener K., Aldemir M., Ik E., Okulu E., zcan M.F., Uurlu M., Tangal S., zayar A

The extracted data included characteristics of the study cohort, study design, details of specific interventions (drugs and dosing) and pharmacokinetic outcomes