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Other studies have found that the activation of NLRP3 can recruit and activate pro-inflammatory protease caspase-1, and then produce IL-1, IL-18 and other cytokines, triggering a process of inflammation-relatedcell death named pyroptosis

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In brief, 4 mg of ginsenosides (equivalent to 40 mg of Panax ginseng dry extract) was dissolved in 0.75 ml deionized water for preparation of the dose for young adult rats (Sample A), and 7 mg of ginsenosides (equivalent to 70 mg of Panax ginseng dry extract) was dissolved in 0.75 ml deionized water for preparation of the dose for aged adult rats (Sample B)

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