Continuous monitoring of patient outcomes and post-marketing surveillance will help ensure that these therapies are used safely and effectively
Some laboratory studies have shown that GLP-1 analogs may reduce cartilage degradation and synovial inflammation in experimental arthritis models
The most common side effects of GLP-1 receptor agonists include nausea, vomiting, diarrhoea, constipation, and abdominal discomfort , particularly during the initial weeks of treatment or following dose escalation
Retatrutide is the potential new champion of efficacy, offering a distinct advantage in specific metabolic comorbidities, particularly liver health, due to its GIP GLP-1 Glucagon agonist structure
Retatrutide produced 28.328.7% average weight loss in Phase 3
Mechanism: Retatrutide is a triple agonist that targets GLP-1, GIP, and glucagon receptors