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In summary, alterations at the glutathione activator site result in an absent geometric and electrostatic complementary 3,50 for the reducing agent, explaining the inefficient reduction of numerous glutaredoxins 12,25,26,27,28,29,48 and thioredoxins by GSH

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This tripeptide, composed of three amino acidsglutamine, glycine, and cysteineserves as a critical player in combating oxidative stress and maintaining cellular health

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