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6e) showed that APP/PS1 mice treated with ITP-LNP/siBACE1 and the WT (saline-treated) mice could repeatedly find the platform in the target quadrant, and the number of platform crossings, the length of the platform, and the length of the target quadrant were significantly greater than those of the mice given LNP/siBACE1, ITP-LNP/siScr, or LNP/siScr

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Common side effects are gastrointestinal including nausea, vomiting, and diarrhoea and are most pronounced during dose escalation

High-quality, lean protein sources are less likely to trigger digestive upset

The term scatter factor was later introduced independently in 1985 by Stoker and co-workers, as they discovered a protein interrupting the intracellular junctions of epithelial cells thereby promoting their migration in a paracrine manner and promoting an invasive phenotype [4]

10.1016/j.bbrc.2012.07.086