OPTION-DM was a multicentre, randomised, double-blind, crossover trial in patients with DPN
As the 16-methyl analogue of cortisol, it possesses roughly 25-fold greater anti-inflammatory potency yet virtually no mineralocorticoid activity, allowing clinicians to achieve strong glucocorticoid effects without problematic sodium retention
This dual action not only enhances the body's ability to manage blood sugar but also significantly affects weight loss by reducing appetite and caloric intake
It works by mimicking the effects of a naturally occurring hormone in the body called GLP-1, which helps to regulate appetite and decrease food intake
They can facilitate easier weight loss, provide personalized care, and generate increased motivation towards dietary changes
Since you are eating less, your body might try to save energy by making you lethargic