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Regulatory Toxicology and Pharmacology , 114, 104665
Results at 68 weeks: 40.4% of CagriSema participants lost 25% or more of their body weight 91.9% lost at least 5% Blood pressure fell by 10.9 mmHg systolic on average About 40% of participants reduced or stopped blood pressure medications 87.7% of those with prediabetes at baseline achieved normal blood sugar Results were published in the New England Journal of Medicine and presented at the American Diabetes Associations 2026 Scientific Sessions
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What were building Neurophorol to enable (research-stage endpoints): receptor/pathway profiling + SAR learning neuroimmune and inflammation readouts oxidative stress / resilience markers reproducible preclinical validation workflows Were opening collaboration discussions with teams who can help validate and translate this platform responsibly: (Universities, Biotech companies, Tribal communities, and Investors) CB1/CB2 functional assays + signaling bias analytical chemistry (LCMS/NMR) + stability profiling neuroimmune models (microglia), biomarkers, preclinical design ADME/PK and translational study frameworks If you work in this space, comment NEUROPHOROL or DM your capability stack
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