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One study in diet-induced obese mice found that an NNMT inhibitor combined with a calorie-restricted diet was associated with shifts in gut bacterial populations, suggesting metabolic intervention can have knock-on effects on gut composition

INTRODUCTION Despite being considered one the safest pharmaceuticals, paracetamol/acetaminophen (N-acetyl-p-aminophenol, APAP) overdose is one of the most important causes of drug-induced liver injury, that can eventually lead to acute liver failure (ALF) ( 1, 2 )

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Levothyroxine dosing is often related to body weight