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Bearing in mind an estimated 8-10% prevalence of vitamin B12 deficiency among the population of this age group, an initial sample of 3556 patients will need to be recruited

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The FDA-approved formulation contains only tirzepatide as the active ingredient, along with inactive excipients such as sodium chloride, sodium phosphate, and water for injection

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An important point to consider when using T cell-involving antibodies is that the tumor microenvironment is immunosuppressive, and the infiltrated T cells are mostly exhausted