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From Phase 3 start to final obesity approval was roughly four years, and from NDA submission to first approval was about seven months under priority review

Skipping titration steps or escalating faster than every four weeks significantly increases discontinuation rates due to intolerable GI symptoms

doi: 10.1038/ajg.2012.373

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Key Takeaways Lyophilized BPC-157 tolerates brief room temperature exposure (up to 48 hours at 25C) with less than 10% potency loss, while reconstituted peptides lose 2530% potency in the same timeframe