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Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin

| 05.15.26 | 10 min read

These cross-links distort the DNA structure and subsequently prevent DNA synthesis and replication in rapidly proliferating cancer cells (Dugbartey et al., 2016) (Figure 1)

National Library of Medicine [Internet]

Sci Adv 10:eadi4819

This is important for the development of vascular lesion because it shows that G6PD deficiency, while reducing the reactive nitrogen species, actually increases the production of ROSs that exert much more deleterious effects than NO itself [46]