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Compounded drugs have not been reviewed by the FDA for safety, efficacy, or manufacturing quality

This dual mechanism makes it particularly effective at: Reducing appetite Slowing gastric emptying Improving insulin sensitivity Clinical trials such as the SURMOUNT-1 trial demonstrated that tirzepatide delivered an average weight loss of up to 20.9% of body weight over 72 weeks, making it one of the most effective weight loss medications currently available in the UK

This once weekly injection of (GLP-1) receptor agonist will be available in 0.5-mg and 1.0-mg doses, via a dedicated prefilled pen device

Funding This study was not supported by any funding

three to four if schedule allows Add or increase EAA supplementation Particularly around training and between meals when appetite suppression limits food intake Assess sleep quality Inadequate sleep increases cortisol and muscle catabolism

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