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It may also increase heart rate and blood pressure

These signs may indicate that discontinuation is not appropriate at this time or that a different weaning approach is needed

In recent years, GLP-1 medications have become a focal point in the medical community due to their innovative treatment mechanisms, significant therapeutic efficacy, and broad development prospects

While native GLP-1 contributes to normal glucose regulation, semaglutide produces receptor activation at levels that exceed endogenous postprandial GLP-1 concentrations, generating clinically significant HbA1c reduction and weight loss

Oral administration of GSH is not very effective, however, because it is poorly absorbed through digestion and insufficient amounts cross the blood-brain barrier

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