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Starting at the lower 0.75 mg dose and gradually increasing also improves tolerability, and most gastrointestinal side effects diminish after several weeks

Between 50% and 57% of those on the highest dose achieved 20% or greater weight loss

Most cases are mild to moderate in severity and tend to diminish over time as tolerance develops, though some patients may experience persistent symptoms requiring management strategies

Most people can skip the gradual transition and just delay their injection by the full amount in one week, but if you are particularly sensitive to dosing changes or are in a dose escalation phase, the gradual approach provides an extra safety margin

Updated: 2 hours ago The Woodchucks and Rafters battle it out in Wisconsin Rapids on Monday

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