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In septic mice, semaglutide attenuated sickness behavior, hypothermia, systemic inflammation, and lung injury through the downregulation of pro-inflammatory cytokines (TNF- , IL-1, IL-6, CXCL1), suppression of neutrophil infiltration, and decreased expression of genes associated with tissue remodeling and inflammation (Mmp9, Timp1, Ly6g)

What many people dont realize, however, is that the body already produces GLP-1 naturally

There are a couple of moving pieces here: nutrition, hormones, and stress

For patients who want to reduce their dose after reaching goal weight, a gradual tapering approach works best

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Tirzepatide is an approved GLP-1R/GIP dual agonist developed by Eli Lilly, garnering significant attention alongside SEMA in the field of T2DM and weight loss