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It works by stimulating the bodys hormonal signals rather than directly increasing blood flow to the penis

Results: We observed a significant decrease in fasting plasma glucose, HbA1c, weight, BMI, waist circumference

This hormonal signaling reduces the frequency and intensity of hunger signals, helping patients naturally reduce caloric intake

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Critical limitations identified in the systematic review include predominant use of small rodent models (primarily rats), short follow-up periods relative to human healing timelines, variable dosing regimens complicating dose-response assessment, and lack of standardized outcome measures across studies