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Importantly, the nonglycosylated band 3 was not stabilized by Kifunensine treatment, underscoring the importance of glycosylation in EDEM-dependent ER protein degradation

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In contrast to the experiments using resting cells where ATP was added into the reaction system, the higher GSH production and yield in the fed-batch cultures of ZJ124345 compared to ZJ1234 indicated that the deletion of glgB led to an improved ATP supply ability