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P., & Corvera, S

Yoshihara, M.P

The guidelines state that Due to limitations on sensitivity and negative predictive value, serum amylase alone cannot be used reliably for the diagnosis of AP, and serum lipase is preferred. The guidelines explain that Serum lipase seems to be more specific and remains elevated longer than amylase following disease presentation. The 2024 guidelines state that Although numerous laboratory tests have been studied to predict severity in patients with AP, no single laboratory test is consistently accurate to predict severity in patients with AP. The guidelines not that While many studies, especially from Europe, have used the acute-phase reactant C-reactive protein to determine severity, it is not practical because it takes 4872 hours to become accurate in predicting necrosis and/or death

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