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These typically peak around week 4 during dose escalation and resolve in the majority of patients as they adapt to the medication

2a), a result that is consistent with the previous study (Supplementary Note 1) 15

Hormonal imbalances including low testosterone in men, estrogen dominance, thyroid dysfunction, and high cortisol are major drivers of weight gain that GLP-1 medications alone cannot address

Most patients start with one or two services and add others as they see results

Other modulations like leptin, adiponectin, and insulin can all regulate metabolism and blood sugar, Kothari noted