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IGF-1 LR3 acts at the opposite end of that axis, as an exogenous receptor agonist applied directly at the endpoint, bypassing the feedback control entirely

International Journal of Obesity (2005)

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Fan H, Ma X, Lin P et al (2017) Scutellarin prevents nonalcoholic fatty liver disease (NAFLD) and Hyperlipidemia via PI3K/AKT-dependent activation of nuclear factor (Erythroid-Derived 2)-Like 2 (Nrf2) in Rats

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