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Tofacitinib, an inhibitor of inflammatory enzymes associated with RA, has recently been reported to prevent cytokine-induced gut barrier dysfunction as well as limiting the delocalisation of TJ proteins, such as ZO-1, in IECs following exposure to IFN- (Sayoc-Becerra et al

These effects can be tissue-specific and depend on dopamine concentration and receptor subtype activation

By boosting this enzyme, the peptide provides ongoing protection against oxidative damage

Matsushima, T

Peptides from different classes should generally be kept in separate syringes