[12] This mechanism slows gastric emptying (most notably early in therapy), prolongs feelings of fullness, and reduces hunger signals in the brain , leading to decreased food intake and subsequent weight loss
To achieve this, it will be necessary to complement chemical studies with more comprehensive biological evaluations, including more complex cell models, detailed mechanistic studies, pharmacokinetic analyses, and in vivo assessments
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The average patient age was 75 years (range: 23 to 102 years)
These features offer convenience and possibly better adherence
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