Epub 2024 Jun 27
The self-reported member outcome referenced on the SkinnyRx website is based on data from a specific subset of members and is not a guarantee of outcomes for any individual enrollee
More recently, the SUMMIT trial demonstrated that tirzepatide reduced the composite risk of cardiovascular death or worsening heart failure by 38% (HR = 0.62, 95% CI: 0.410.95) in patients with heart failure with preserved ejection fraction (HFpEF) and a BMI 30 kg/m 2 , 32% of whom also had type 2 diabetes
So any product claiming to be this drug outside authorised trials is almost certainly counterfeit, mis-labelled, dosed incorrectly, or contaminated
The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology
Tirzepatide (Mounjaro, Zepbound, compounded) Tirzepatide dual GIP/GLP-1 mechanism produces robust weight loss and glycemic control, but the shorter half-life means slightly less flexibility in timing