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From a clinical translation viewpoint, the most major challenge for aptamer medicines is their stability, particularly their sensitivity to fast nuclease breakdown and renal clearance

Thereafter 34 mice were treated every 24 h for three successive days with either saline alone (control), saline with IL-13, saline with GGsTop, or saline with IL-13 and GGsTop

It indicates that the patient has type 2 diabetes with suboptimal glycemic control, which provides strong medical necessity for adding or adjusting medication

R., Palamara A

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To model wound healing, angiogenesis, and inflammatory-pathway modulation in preclinical studies