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Morgan AS, Sanderson PE, Borch RF, Tew KD, Niktsu Y, Takayana T, VonHoff DD, Izbicka E, Mangold G, Paul C, Broberg U, Mannervik B, Henner DW and Kauvar LM

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Factors include body weight, hydration status, kidney function, and administration route

Tirzepatide and GIP treatment lead to significantly lower interleukin-1 beta (IL1B) levels and Tirzepatide further lowered interleukin-6 (IL-6) and monocyte-chemoattractant protein-1 (MCP-1) levels, highlighting distinct tissue-specific regulatory roles in pancreatic adipose tissue metabolism and inflammation [32]

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