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While it was long assumed that patients simply suffered from systemic glutathione depletion, a landmark 2025 study published in the Proceedings of the National Academy of Sciences (PNAS) uncovered a more complex reality

Once DRP1 oligomerizes on the OMM and activates its GTPase activity, GTP hydrolysis triggers a conformational change

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[DOI] [PubMed] [Google Scholar] 6.Alkhezi O.S., Alahmed A.A., Alfayez O.M., Alzuman O.A., Almutairi A.R., Almohammed O.A

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