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Yes, SGLT2 inhibitors should be temporarily discontinued 3 days before major surgical procedures requiring fasting and during acute illness, particularly if experiencing reduced food intake, dehydration, or persistent vomiting

Effectiveness: Slower onset of results compared to IV therapy due to lower bioavailability

In addition to agonists only target to GLP-1 receptors, agonists with multiple targets now are being developed

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Roles of regulatory T cells in cancer immunity