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2A R antagonists can improve motor dysfunction in patients with PD as monotherapy or in combination with L-DOPA and other antiparkinsonian drugs (Table 1) [57,58]

However, it is currently unclear and to what extent the differences observed in CVOT reflect the heterogeneous pharmacological properties of each drug in the GLP-1RA category

This has led many functional medicine practitioners to seek alternative delivery methods that can bypass the destructive environment of the stomach and deliver the intact molecule directly to the cells that desperately need it

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Montrose-Rafizadeh, G