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American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update

In response to cell invasion, the transcription factor Nrf2 is activated to defend cells from damage

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This cascade promotes vasodilation and improved blood flow to injured tissues

It is involved in the elimination of numerous waste products and toxins , preventing them from accumulating and causing negative effects

This preference shift supports the theory that GLP-1 class medications fundamentally alter food reward processing in the brain, not just hunger signaling