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Growth hormone-related therapies should be avoided in active malignancy, as growth hormone may promote tumor growth

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Therefore, these findings support a detrimental role of HO-1 activation in the settings of sI/R and doxorubicin insults, where HO-1 is markedly upregulated, by promoting ferroptosis of cardiomyocytes

Experimental studies suggest that the peptide may influence the secretion of hormones, and a possible mechanism of action involving the modulation of adrenergic transmission has been proposed