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N Engl J Med (2019) 381(9):84151

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Loss of appetite and nausea can make people eat less food, which can cause nutrient deficiencies and hair loss

This is why the weight loss results are so dramatic

Both mechanisms increase cytoplasmic concentrations of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), producing a cytoplasmic surge of monoamines

Critics warn that loosening the HON rule could lead to persistent and increased EtO exposure, especially among vulnerable populations, reversing recent public health gains