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For mouse studies, at least 3 independent experiments were carried out using different mice

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PMID 29260458

Kolwicz SC Jr, Olson DP, Marney LC, Garcia-Menendez L, Synovec RE, Tian R (2012) Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy

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PDK: pyruvate dehydrogenase kinase