For patients with complex chronic illnesses who often already suffer from irritable bowel syndrome (IBS), mast cell activation syndrome (MCAS), or general gut sensitivity, this laxative effect is entirely counterproductive and can lead to further dehydration and electrolyte imbalance
Available from: Novo Nordisk, Wegovy
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Lyophilized peptides are far more temperature-stable and can handle short periods outside refrigeration
These may occur with or without pain, and, as with other injection site reactions, usually go away on their own within a few days
Thermal degradation Thermal degradation refers to the case where the polymer, at elevated temperatures, starts to undergo chemical changes without the simultaneous involvement of another compound Guaita et al