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Serious adverse events are not reported in the literature

Choosing the Right Needle Size Factors to Consider : Patient's Body Type : Thinner individuals may require shorter needles to avoid penetrating the muscle during SC injections, while individuals with more muscle mass may need longer needles for effective IM injections

Injections are necessary when your body cannot properly absorb vitamin B12 from your digestive system

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[9] [2] According to NICE guidance, patients with confirmed B12 deficiency and neurological involvement typically require more frequent initial dosing (alternate-day injections) until symptom improvement occurs