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Structural features of active, Cagri-bound, AMY1R, AMY2R and AMY3R complexes Overall, the consensus structures of AMYRs bound to Cagri or CagriBB exhibited highly similar backbone conformations of the peptide and CTR subunit (Fig
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The second class of drugs directly inhibits or combines GPX4 to induce ferroptosis, and related drugs include the ferroptosis inducers FIN56 and RSL3, although they have not been clinically applied
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