Copper overload: Theoretically possible with high-dose systemic use, though not documented at typical topical concentrations
This is not typical for IV use, but anyone with asthma should mention it to the provider beforehand
The Nature Scientific Reports 2016 study confirmed that GHK-Cu produced no cytotoxicity to human keratinocytes at concentrations up to 5,800 micromolar over 72 hours and did not induce inflammatory biomarkers
However preferably, the release is sustained such that at least 50 % of copper peptide is released over 24 hrs
I quit taking them after a while
Oxidative stress has been linked to chronic disorders including autoimmune disease, cancer, cardiovascular disease, lung disease, diabetes, fibromyalgia, dementia, and Alzheimers, Staheli says