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#Cardiology #ASCVD #ClinicalResearch #CardiovascularRisk #Obesity #EvidenceBasedMedicine #PrecisionMedicine Evolocumab can help attenuate the elevated risk of major adverse cardiovascular events that individuals with obesity and atherosclerotic cardiovascular disease (ASCVD) face, according to a prespecified analysis from the FOURIER trial published in #JACC

Deployment timing depends on benefit rules and prescribing safeguards

Trends in Endocrinology & Metabolism, 2017

If possible, work with your healthcare provider on a step-down plan that includes nutrition counseling or temporary appetite-support measures

Increased LPCs (16:0, 17:0, 18:0), fatty acids (propionic, stearic, octadecanoic, myristic, oleic and linoleic acid), and decreased ketogenic AAs (isoleucine, leucine, threonine phenylalanine, tyrosine), and SM (20:2) at 24 h after admission predicted unfavorable outcomes at 3 months (Table 2) [30]

Unfortunately, people tend to use it to lighten skin in order to achieve lighter skin tones, and this form of skin bleaching is what has given hydroquinone a bad reputation