While these interactions do not establish direct causality, they provide integrative evidence linking metabolomic alterations to gene networks previously implicated in neurodevelopmental and metabolic regulation
Biochem Pharmacol 43(5):11371141 Peyroche G, Saveanu C, Dauplais M, Lazard M, Beuneu F, Decourty L, Malabat Ch, Jacquier A, Blanquet S, Plateau P (2012) Sodium selenide toxicity is mediated by O2-dependent DNA breaks
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While it is better studied in skin and wound healing contexts, there is emerging preclinical data suggesting GHK-Cu supports extracellular matrix remodeling and anti-inflammatory gene expression in gut tissue
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