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larger volumes give finer dosing granularity at the cost of larger injection volumes

The Phase 2 trial reference point The Phase 2 retatrutide trial (Jastreboff et al., New England Journal of Medicine 2023) enrolled 338 adults across placebo and retatrutide arms at 1, 4, 8, and 12 mg weekly

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If youve gone down any GLP-1 rabbit hole, youve seen both of these names