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Histopathological examination is the key and would show granular deposits of yellow-brown pigment and no inflammation

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They are usually used only for a short period of time, since prolonged NSAID use can lead to unwanted effects on the body like stomach ulcers and bleeding within the gastrointestinal tract

In addition, clinical trials for 77A/G polymorphism of MMP-13 and risk for developing knee OA are currently being conducted in the Greek population [66]

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